Going for Broke: Dopamine Influences Risky Choice
نویسندگان
چکیده
Dopamine neurons track reward by increasing or decreasing their firing rate when a reward is present or absent. In this issue of Neuron, Stopper et al. (2014) demonstrate that artificially eliminating these dopamine bursts or dips can alter risky decision-making.
منابع مشابه
Going for Broke and Playing it Safe: Dynamic Competition with Choice of Variance
We consider a differential game, in which the joint choices of the two players influences the variance, but not the mean, of the one-dimensional state variable. We interpret this state variable as a summary of how far ‘ahead’ player 1 is in the game. The flow payoffs that the players enjoy are a continuous, monotonic and bounded function of this state variable. In any Markov Perfect Equilibrium...
متن کاملDopaminergic drugs decrease loss aversion in Parkinson’s disease with but not without depression
Acknowledgements This project was funded by a grant from the " Stichting Parkinson Fonds " , Hoofddorp, the Netherlands. We would like to thank all participants for their cooperation in the study. Abstract 1 Depression, a common non-motor symptom of Parkinson's disease (PD), is accompanied by impaired 2 decision making and an enhanced response to aversive outcomes. Current strategies to treat d...
متن کاملDecisions from Experience: Adaptive Information Search and Choice in Younger and Older Adults
In real-world decision making, choice outcomes, and their probabilities are often not known a priori but must be learned from experience. The dopamine hypothesis of cognitive aging predicts that component processes of experience-based decision making (information search and stimulus-reward association learning) decline with age. Many existing studies in this domain have used complex neuropsycho...
متن کاملDopaminergic Modulation of Risk-based
Psychopharmacological studies have implicated the mesolimbic dopamine (DA) system in the mediation of cost/benefit evaluations about effort-related costs associated with larger rewards. However, the role of DA in risk-based decision making remains relatively unexplored. The present study investigated how systemic manipulations of DA transmission affect risky choice assessed with a probabilistic...
متن کاملAdolescent Intermittent Ethanol Exposure Is Associated with Increased Risky Choice and Decreased Dopaminergic and Cholinergic Neuron Markers in Adult Rats
BACKGROUND Binge drinking is prevalent during adolescence and may have effects on the adult brain and behavior. The present study investigated whether adolescent intermittent ethanol exposure alters adult risky choice and prefrontal dopaminergic and forebrain cholinergic neuronal marker levels in male Wistar rats. METHODS Adolescent (postnatal day 28-53) rats were administered 5 g/kg of 25% (...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Neuron
دوره 84 شماره
صفحات -
تاریخ انتشار 2014